Iron Cytotoxicity in Chronic Hepatitis C.
نویسندگان
چکیده
منابع مشابه
Serum Iron Markers in Patients With Chronic Hepatitis C Infection
BACKGROUND Patients with chronic hepatitis C (CHC) often have elevated serum iron markers, which may worsen liver injury. OBJECTIVES The aim of this study was to investigate the possible correlations between iron metabolism serum markers, HCV viral load, and liver disease severity in treatment-naive patients with chronic hepatitis C infection. PATIENTS AND METHODS Eighty five patients with ...
متن کاملserum iron markers in patients with chronic hepatitis c infection
conclusions this study revealed that serum iron markers (especially ferritin and transferrin) might be used as surrogate markers for both liver fibrosis and necroinflammatory activity. patients and methods eighty five patients with untreated hepatitis c chronic infection were investigated. . results twenty one patients (24.7%) had elevated serum iron levels, and 29 subjects (34.1%) had severe l...
متن کامل[HFE gene mutations, hepatic iron content, and histological severity in hepatitis C virus-induced chronic hepatitis].
OBJECTIVE To study whether any relationship exists between the C282Y and H63D mutations of the HFE gene, iron liver content, and the severity of histological damage in patients with hepatitis C virus (HCV)-induced chronic hepatitis. MATERIAL AND METHODS In 72 patients diagnosed with HCV-chronic infection, naïve for antiviral therapy, and undergoing liver biopsy, the Knodell index was establis...
متن کاملREVIEW Hepatitis C and Iron
Hepatitis C is the commonest form of chronic viral hepatitis in most western countries. A significant proportion of patients develop cirrhosis, hepatic failure and hepatocellular carcinoma. The results of controlled trials have shown that interferon a is an effective treatment for hepatitis C. Treatment results in normalization of elevated transaminase levels in up to 50% of patients, although ...
متن کاملHepatitis C Virus Genotyping in Chronic Hepatitis C Patients
Chronic hepatitis C virus infection is a massive worldwide healthcare burden with estimated costs in the USA alone of over $5 billon per annum. The virus has a 9.5kb positive sense single-stranded RNA genome with striking heterogeneity between isolates, which has led to it being divided into 6 genotypes and more than 50 subtypes and many quasispecies that has been arisen due to the infidelity o...
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ژورنال
عنوان ژورنال: Journal of Health Science
سال: 2002
ISSN: 1344-9702,1347-5207
DOI: 10.1248/jhs.48.227